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KMID : 0363319760010010035
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Journal of Korean Oriental Internal Medicine
1976 Volume.1 No. 1 p.35 ~ p.43
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STUDIES ON THE EFFECT OF THE BUPLEURI RADIX ON THE SERUM TRANSAMINASE ACTIVITIES AND THE CONTENTS OF TOTAL CHOLESTEROL IN SERUM FROM THE ALLOXAN-DIABETIC RABBITS
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Abstract
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The effects of root of the Bupleurum falcatum.L. on the serum transaminase (SGP-T, SGO-T) activities and the content of total cholesterol in serum from normal and alloxan-diabetic rabbits were observed.
The preparations were extracted by methanol, and extracted samples were orally administrated to the normal and alloxandiabetic rabbits.
The transaminase activities and the content of total cholesterol in serum of normal rabbits were significantly increased by administration of the alloxan.
The increased serum transaminase activities of the alloxandiabetic rabbits were significantly decreased after 96 hours by administration of the extracted samples.
The increased content of total cholesterol in serum of the alloxan-diabetic rabbits were gradually decreased by administration of the extracted samples and were recovered to the control levels after 12 days.
According to the above results, it would be concluded that the extract of Bupleuri Radix influences for the recovery of the increased contents of total cholesterol and serum transaminase activities by alloxan.
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